Anti-FRMD2抗体FRMPD1 has been identified as a regulatory binding partner of activator of G-protein signaling 3 （AGS3）.

产品编号 yb-8233R
英文名称 Anti-FRMD2抗体
中文名称 FRMD2蛋白抗体
别    名 FERM and PDZ domain containing protein 1; FERM domain containing protein 2; FRMD2; KIAA0967; FRPD1_HUMAN.
Anti-FRMD2抗体 
说 明 书 0.2ml  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Horse, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 173kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FRMD2/FRMPD1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
FRMPD1 has been identified as a regulatory binding partner of activator of G-protein signaling 3 (AGS3).

Function:
Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. 

Subunit:
Interacts with GPSM1.

Subcellular Location:
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found both in the cytoplasm and associated with the cell membrane. 

Similarity:
Contains 1 FERM domain. 
Contains 1 PDZ (DHR) domain.

Database links:
UniProtKB/Swiss-Prot: Q5SYB0.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.