Anti-Fetuin A/AHSG抗体Alpha2-HS glycoprotein （AHSG）, a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule

产品编号yb-2922R
英文名称Anti-Fetuin A/AHSG抗体
中文名称 胎球蛋白A
别    名 Fetuin-A; 59 kDa bone sialic acid containing protein; A2HS; Aa2 066; AHS; AHSG; Alpha 2 HS glycoprotein; Alpha 2 HS glycoprotein chain A; Alpha 2 Z globulin; Alpha 2HS glycoprotein; alpha2 Heremans Schmid glycoprotein; Asialofetuin; Ba alpha 2 glycoprotein; BSP; Countertrypin; FETUA; Fetuin A; Fetuin, mouse, homolog of ; FetuinA; Glycoprotein PP63; HSGA; pp63; Alpha-2-HS-glycoprotein chain A
Anti-Fetuin A/AHSG抗体 
说 明 书 0.1ml  0.2ml  
研究领域 免疫学  神经生物学  信号转导  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Alpha-2-HS-glycoprotein chain A.
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008]

Function:
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

Subunit:
Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond.

Subcellular Location:
Secreted.

Tissue Specificity:
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.