Anti-FGF22抗体FGF22 is a member of the fibroblast growth factor （FGF） family. FGF family members possess broad mitogenic

产品编号 yb-5773R
英文名称Anti-FGF22抗体
中文名称 成纤维细胞生长因子22抗体
别    名 FGF 22; FGF-22; FGF22; FGF22_HUMAN; Fibroblast growth factor 22; si:dkey 21e2.2.
Anti-FGF22抗体 
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  心血管  免疫学  信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Cow, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FGF22.
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
FGF22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Fibroblast Growth Factor-22 stimulates the proliferation and activation of cells that express FGF receptor.

Function:
Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.

Subunit:
Interacts with FGFR1 and FGFR2. Interacts with FGFBP1. 

Subcellular Location:
Secreted (Potential). 

Similarity:
Belongs to the heparin-binding growth factors family.