Anti-Arg3.1抗体该蛋白与大脑的学习记忆有关，研究人员认为：是ARC蛋白通过加强了突触的功能从而储存了这些记忆，包括情感和学习记忆。
目前，科学家也将该蛋白用于吸食成瘾性的研究。

产品编号 yb-0385R
英文名称 Anti-Arg3.1抗体
中文名称 即刻早期基因ARC抗体
别    名 ARC; ARG3.1; Arc; Arg 3.1; Activity regulated cytoskeletal associated protein; Activity regulated cytoskeletal protein; Activity-regulated cytoskeleton-associated protein; Activity regulated cytoskeletal-associated protein; ARC/ARG3.1; Activity-regulated gene 3.1 protein homolog; Activity regulated gene 3.1 protein homolog; Arg3.1; KIAA0278; ARC_HUMAN; growth factor ARC.
Anti-Arg3.1抗体   
说 明 书 0.1ml  0.2ml  
研究领域 细胞生物  神经生物学  细胞类型标志物  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARC
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Activity-regulated cytoskeleton-associated protein （ARC）in the brain and learning and memory, researchers believe: ARC protein is by strengthening the function of synaptic links in order to save the memory, including learning and memory and emotion. At present, the scientists will also Activity-regulated cytoskeleton-associated protein used to take drugs addiction.

Function:
Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.

Subunit:
Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.

Subcellular Location:
Cytoplasm, cytoskeleton. Endosome. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse.

Similarity:
Belongs to the ARC/ARG3.1 family.


该蛋白与大脑的学习记忆有关，研究人员认为：是ARC蛋白通过加强了突触的功能从而储存了这些记忆，包括情感和学习记忆。
目前，科学家也将该蛋白用于吸食成瘾性的研究。