Anti-FAM129A抗体Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A,

产品编号 yb-6534R
英文名称 Anti-FAM129A抗体
中文名称 细胞生长抑制基因39蛋白抗体
别    名 Cell growth inhibiting gene 39 protein; Protein FAM129A; Protein Niban; NIBAN_HUMAN.
Anti-FAM129A抗体 
说 明 书 0.2ml  
研究领域 肿瘤  生长因子和激素  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Horse, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 103kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAM129A/Cell growth inhibiting gene 39 protein (466-500aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response 

Function:
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
xpressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney. 

Similarity:
Belongs to the Niban family. 

Database links:
UniProtKB/Swiss-Prot: Q9BZQ8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.