Anti-FGF17抗体FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction

产品编号 yb-5770R
英文名称 Anti-FGF17抗体
中文名称 成纤维细胞生长因子17抗体
别    名 FGF17; FGF-17; FGF 17; Fibroblast growth factor 17; FGF17_HUMAN.
Anti-FGF17抗体    
说 明 书 0.1ml  0.2ml  
研究领域 肿瘤  心血管  免疫学  信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human FGF17
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction and patterning of the embryonic brain and is preferentially expressed in the embryonic brain. There are two named isoforms.

Function:
Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development. 

Subunit:
Interacts with FGFR3 and FGFR4. 

Subcellular Location:
Secreted. 

Tissue Specificity:
Preferentially expressed in the embryonic brain. 

Similarity:
Belongs to the heparin-binding growth factors family.